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Isotretinoin

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Isotretinoin Description
Isotretinoin is a tablet prescribed for treating severe rosacea.
It's a form of vitamin A that helps to decrease inflammation and reduce oil production in the skin.
You might need to wait a few weeks to notice any results, and the treatment usually lasts between 16 and 24 weeks.

What is Isotretinoin?

Isotretinoin is a strong medication sometimes used to treat rosacea, a skin condition that leads to redness and bumps on the face. It works by reducing inflammation, which can help improve your symptoms. It's especially effective for severe cases, particularly when used alongside a corticosteroid.

It's made from Vitamin A and is a type of treatment known as a retinoid. Retinoids are typically used when antibiotics or other treatments haven't been successful. It's crucial to use effective contraception while taking Isotretinoin, as it can lead to serious birth defects in an unborn baby. Because of this, and other reasons, a dermatologist must closely monitor treatment with Isotretinoin.

How does Isotretinoin work?

Isotretinoin, a type of tretinoin used for acne, can also help with rosacea by lessening the redness and bumps on your face. It works by reducing the size of the oil glands in your skin and calming the inflammation that causes redness. This results in fewer breakouts and generally better-looking skin. While it may take a while to notice the full benefits, isotretinoin can be highly effective for rosacea when used as your doctor advises.

What doses of Isotretinoin are available?

Isotretinoin is available in three different strengths: 5mg, 10mg, and 20mg. The 5mg capsules are a pale pink or cream colour, the 10mg capsules are light pink, and the 20mg capsules are a reddish-orange shade.

How long does Isotretinoin take to work?

When you begin taking oral Isotretinoin, it might appear that your skin condition is getting worse, but you should notice improvement within a week to ten days. Typically, just one course of treatment is needed, lasting between 16 and 24 weeks, depending on how severe your symptoms are.

How well does Isotretinoin work?

Isotretinoin has been studied since the 1980s and is known to be very effective in treating rosacea. In a study focusing on severe rosacea, a 20-week course of oral isotretinoin showed great effectiveness. Experts believe it works by reducing blood flow to the face and shrinking the sebaceous glands.

What should I do if I accidentally use Isotretinoin incorrectly?

If you or someone else accidentally takes too many capsules, get urgent medical help straight away.

If you forget to take a dose, have it as soon as you remember. However, if it's nearly time for your next dose, just skip the missed one and carry on as normal. Avoid taking two doses to make up for the one you missed.

Will Isotretinoin affect my mood?

Mood changes are a very rare side effect of Isotretinoin, with only a 1 in 1000 chance of occurring. Despite this low risk, it's crucial for your clinician to keep a close eye on your treatment. More research is needed to fully understand the connection between isotretinoin and psychiatric side effects.

In reality, treatment with Isotretinoin is more likely to boost your mood. A study showed that most participants experienced better mental well-being, although a small number did notice a decline in their mood.

If you've experienced mood disorders in the past, be sure to inform your clinician before starting Isotretinoin.

What other side effects can I get from Isotretinoin?

As with all medicines, Isotretinoin may cause side effects, although not everyone will experience them. Some common side effects are:

To see all possible side effects, have a look at the leaflet included with your medication.

Are there any similar treatments to Isotretinoin?

There are treatments similar to Isotretinoin that also have anti-inflammatory effects. For instance, brimonidine and ivermectin can both help lessen the redness and swelling associated with rosacea.

Some people might assume tretinoin and isotretinoin are the same since they're both derived from vitamin A. Despite their similar names, they're actually prescribed for different purposes and used differently. Tretinoin is a topical treatment for mild to moderate acne. It works by speeding up the life cycle of skin cells, helping to keep pores clear. It can also be applied to the skin to treat wrinkles and sun damage, or taken orally, alongside other medicines, to treat leukaemia.

Can I take Isotretinoin whilst pregnant?

No, it's crucial not to become pregnant while on this medication because it can harm your unborn baby. It's known to be teratogenic, which means it can cause serious birth defects and may raise the risk of miscarriage. You should also avoid taking it if you're breastfeeding, as it can pass into the milk.

To stay safe, use a reliable form of contraception while you're on treatment and for a month after finishing it. It's important to take regular pregnancy tests, and if you think you might be pregnant at any time, stop the treatment immediately. Your clinician will keep a close eye on you throughout your treatment to ensure it's safe and appropriate for you.

Do I need a prescription for Isotretinoin?

Yes, you'll need a prescription to take Isotretinoin, as it's a strong medication. Your prescriber will review your medical history to make sure it's safe for you and to confirm that you've already tried other treatments for your rosacea.

Important Information

Isotretinoin isn't right for everyone, and there are a few important things you should know when taking it.

Here's all the official information about it. If there's anything you don't understand, please let our clinician know, and they can discuss it with you.

Always Read The Patient Information Leaflet

Medicines can cause side effects. Always read the leaflet that comes with your medication and report any side effects to your pharmacist. Stay informed—order safely today!

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