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Silkis

£79.95

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Silkis Description
Silkis is an ointment applied to the skin for treating psoriasis, and it contains a form of vitamin D.
It helps slow down the quick production of skin cells that leads to psoriasis.
Apply a thin layer of ointment twice daily.

What is Silkis?

Silkis is an ointment applied to the skin that contains calcitriol, a form of vitamin D. It's used for treating mild to moderate psoriasis. Psoriasis occurs when your body makes skin cells too rapidly, and Silkis helps slow down this overproduction of skin cells.

Silkis is only available with a prescription, so a clinician must ensure it's safe for you before use. Share details about your health in our online consultation, and we'll let you know if Silkis is suitable for you – and prescribe it if it is.

How does Silkis work?

Silkis contains calcitriol as its active ingredient, which is a form of vitamin D. This means it works on the vitamin D receptor to control how cells grow, what roles they perform, and how the immune system functions. It helps slow down the fast growth of skin cells, which can reduce the scaling and plaques associated with psoriasis.

Research over both long and short periods has shown that calcitriol is effective in treating psoriasis and carries a low risk of side effects. It can also be used alongside corticosteroids, another psoriasis treatment, to allow for a reduced corticosteroid dose, which in turn lowers the risk of side effects associated with them.

Are there different forms of Silkis?

Silkis is available solely as an ointment, with each gram containing 3 micrograms of calcitriol. If you feel that Silkis isn't the right strength for your psoriasis, whether too weak or too strong, have a chat with your clinician about other treatment options.

How is Silkis different from other treatments for psoriasis?

Silkis is a treatment for psoriasis that contains only vitamin D. For more moderate to severe cases, there are treatments available that combine corticosteroids with vitamin D. Vitamin D helps slow down the production of new skin cells, while the corticosteroid works by 'turning off' the genes responsible for inflammation.

Corticosteroids work by reducing inflammation, which should help relieve psoriasis symptoms, while vitamin D addresses the underlying cause. Studies indicate that vitamin D can enhance the effectiveness of corticosteroids when used together, allowing you to use a lower dose of steroids and for a shorter period.

If you're seeking an alternative treatment for mild to moderate psoriasis, you might consider a coal tar product like Psoriderm or Evorex. Coal tar treatments can help reduce inflammation to ease psoriasis symptoms and also slow down the quick production of new skin cells that cause psoriasis.

They may also cause fewer side effects compared to other psoriasis treatments and can be used alongside other therapies, like phototherapy.

Emollients are another type of topical treatment for psoriasis. These moisturisers help to hydrate your skin, relieve itching and discomfort, and lessen scaling. Using other topical treatments on moisturised skin might make them work better, so you could use an emollient along with another medication.

How well does Silkis work for psoriasis?

Silkis has been shown to be effective and safe for treating psoriasis both in the short and long term. In two clinical trials where participants applied calcitriol or a placebo twice daily, 34% of those using calcitriol saw their psoriasis clear up or reduce to minimal levels. This is compared to 12% and 22.5% in the first and second studies, respectively. Calcitriol also helped reduce symptoms like plaque elevation, scaling, redness, and itching more effectively than the placebo.

Calcitriol ointment rarely causes skin irritation and, unlike some other psoriasis treatments, it doesn't increase your sensitivity to the sun.

Important Information

Silkis isn't right for everyone, and there are a few things you should keep in mind when using it.

Here’s all the official information about it. If anything isn’t clear, just let our clinician know, and they can discuss it with you.

Always Read The Patient Information Leaflet

Medicines can cause side effects. Always read the leaflet that comes with your medication and report any side effects to your pharmacist. Stay informed—order safely today!

Meet our Clinicians

Our expert clinic team reviews your medical information and prescribes safe, effective treatments tailored to your needs

Meet Our Clinicians

  • Oluwole Ososami
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    Superintendent pharmacist with 20+ years of experience. Specialises in acute respiratory diseases, UTIs, musculoskeletal issues, and more

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    Independent Prescribing Pharmacist specialising in ENT, hypertension, and weight loss management

  • Henri Buadi (2059834)

    Independent Clinical Prescribing Pharmacist with expertise in asthma, COPD, and long-term disease management

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